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Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. In contrast to opioids, which bind to µ-opioid receptors in the central nervous technique, conolidine modulates alternate molecular targets. A Science Improvements examine located that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, wh
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" Up to now, the compound has demonstrated remarkably couple, if any, Negative effects, but that is a thing of the double-edged sword. "The dearth of Unwanted side effects makes it an excellent prospect for development," Bohn mentioned. "On the flip side, if there have been Unintended effects, they might offer further clues concerning how the compo